{"id":9377,"date":"2026-08-10T10:18:09","date_gmt":"2026-08-10T10:18:09","guid":{"rendered":"https:\/\/majistraleczacilari.org.tr\/?post_type=docs&p=1966"},"modified":"2026-08-21T11:48:14","modified_gmt":"2026-08-21T11:48:14","password":"","slug":"combinations-of-dermocosmetics-and-magistral-formulations","status":"publish","type":"docs","link":"https:\/\/majistraleczacilari.org.tr\/en\/dokumanlar\/general-articles\/combinations-of-dermocosmetics-and-magistral-formulations\/","title":{"rendered":"Combinations of Dermocosmetics and Magistral Formulations"},"content":{"rendered":"
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Cosmesis”<\/strong>; in the Greek language, means “The Art of Beautification<\/strong>“. The role of cosmetics can generally be defined this way as well. However, today this definition is losing its adequacy; the concept of beauty varies from person to person, and thus we are faced with an incredible variety of cosmetic products.Dermocosmetics<\/em> is a new term that has started to be used in the field of dermatology over the last 20 years. When medications used in the treatment of various skin problems are insufficient, there arose a need for skin, hair, and body care products\u2014namely referred to as \u201cdermocosmetic products\u201d\u2014formulated to be used in addition to medications or on their own to resolve both cosmetic and medical skin concerns, whose formulations, production, quality controls, and clinical trials are conducted as rigorously as pharmaceuticals and based on scientific rules. First produced in 1989 under the brand \u201cMD formulations\u201d, \u201cdermocosmetics<\/strong>\u201d group. Dermocosmetics, whose legal definition is still not clear in many countries including America and Europe, can generally be defined as \u201csubstances and products with biological activity or claimed to have biological activity, which achieve the desired cosmetic result through the physiological effect they display, and positively affect the structure and functions of formations such as skin, hair, and nails\u201d.<\/p>\n

Unlike cosmetics, dermocosmetics are absorbed by deeper layers of the skin and also act on deep layers. Therefore, they are used with the purpose of protecting the skin from potential problems and correcting already existing damage. Another difference from cosmetics is that they continue to maintain their efficacy for a long time after being applied to the skin.<\/p>\n

In order to obtain the \u201cDermocosmetic\u201d label, companies’ products undergo numerous laboratory tests just like pharmaceuticals, and their efficacy, side effects, toxicities (harmful effects), and stability are examined in detail. However, just as there are cosmetics on the market that try to give themselves such an appearance even though they are not dermocosmetics, there are also brands and products that are dermocosmetics but do not declare it. All of these are related to companies’ marketing and sales procedures and tactics. Some cosmetic products, on the other hand, although they are not dermocosmetics, may prefer to remain in the cosmetic class because obtaining the dermocosmetic definition requires a quite costly and lengthy process.Dermocosmetic products are not medicines<\/u><\/strong>. they are not substitutes for medication. However, for many cosmetic skin problems, they can serve as standalone solutions, as well as being used to reduce the adverse effects of pharmacotherapies, support drug treatments, or complement overall therapy. In certain aesthetic skin issues, they can also be sufficient on their own.<\/p>\n

In many countries, the health insurance system reimburses certain dermocosmetic products. For instance, products for conditions such as psoriasis, seborrheic dermatitis, acne, and atopic skin problems, along with certain essential sun protection products, are covered by insurance systems in various countries.<\/p>\n

Dermocosmetic products contain various active ingredients. Therefore, just as there are beneficial effects, the possibility of adverse reactions from these active ingredients also exists.<\/p>\n

Dear Colleagues;<\/p>\n

Products that we refer to as DERMOCOSMETICS are taking an increasing place on the shelves of today’s pharmacies. We will now frequently see these products, whose names we often hear when it comes to skincare in recent years, also being utilized in MAGISTRAL FORMULATIONS..<\/p>\n

In this article, we will examine the ingredients and properties of dermocosmetic products manufactured by various companies in Europe and in our country, and most importantly, the compatibility and maximum ratios we need to know when combining them with active pharmaceutical ingredients used in magistral formulas.NAME<\/strong>Aquabase
\nBiobaseLABORATORY<\/strong>Avene<\/p>\n

Pierre Fabre
\nBiodermaEMULSION TYPE<\/strong>O\/W
\n O\/WINGREDIENTS<\/strong>Ethoxylated cetostearyl alcohol, glycerin monostearate, liquid paraffin, distilled water<\/p>\n

Stearic acid, cetyl alcohol, allantoin, beeswax, distilled water, sorbitan esters, glycosaminoglycans, avocado oil, wheat germ oil, liquid paraffin, proline, glycerol stearate, vitamins A, E,PROPERTIES<\/strong>oil-free cream, fluid, rapidly absorbed, good moisturizing effect, good skin tolerance.
\nNon-comedogenic cream, oil-free, washable, moisturizing, water-dispersible.COMPATIBILITY  % MAX<\/strong>Salicylic acid 5%, erythromycin base 4%, CuSO4<\/sub>5 %, benzoyl peroxide 10 %, etc.
\nAscorbic acid 0.2 %, benzoic acid<\/p>\n

4 %, boric acid 5 %, lactic acid 10 %, retinoic acid<\/p>\n

0.1 %, salicylic acid<\/p>\n

45 %, tartaric acid 3 %, acetazolamide 10 %, alcoholates<\/p>\n

30 %, starch 30 %, etc.<\/p>\n\n<\/table>\n

 
\nNAME<\/strong>C\u00e9rat<\/p>\n

inalt\u00e9rable
\nCobase
\nCold creamLABORATORY<\/strong>La<\/p>\n

Roche-Posay
\nBioderma
\nAvene<\/p>\n

Pierre FabreEMULSION TYPE<\/strong>W\/O
\n O\/W
\n W\/OINGREDIENTS<\/strong>Aluminum silicate 2 g, titanium oxide 2 g, white wax 23 g, liquid paraffin 73 g
\nAqua, sodium laureth sulfate, lauryl glucoside, salicylic acid, sodium lauroyl OAT amino acids, sodium hydroxide, glycol stearate, dimethicone copolyol, hydrogenated talloweth-60 myristyl glycol, PEG-150 distearate, polysorbate 20,<\/p>\n

C 12-15 alkyl lactate, acrylates\/C 10-30 alkyl acrylate crosspolymer, PVP\/dimethylaminoethyl methacrylate copolymer, polyquaternium-10,<\/p>\n

C 12-15 alcohols<\/p>\n

For dry and sensitive skin, oily excipient in the treatment of ichthyosisPROPERTIES<\/strong>Oily ointment, suitable for dry skin, protective.
\nAuxiliary base for magistral formulations, cream base suitable for long-term treatments for dry scalp or other parts of the body.<\/p>\n

Av\u00e8ne thermal spring water, spermaceti, beeswax, liquid paraffinCOMPATIBILITY  % MAX<\/strong>Corticosteroid ointments, salicylic acid 1- 15 %, resorcinol 1- 10 %, coal tar 1- 30 %
\nCoal tar
\nunknown<\/p>\n

\n<\/table>\n

Wishing you a good week\u2026To be continued\u2026<\/strong><\/p>\n

 <\/p>\n

Source<\/strong>Cahiers du pr\u00e9parateur en pharmacie<\/p>\n

Travaux pratiques de pr\u00e9paration et de conditionnement des m\u00e9dicaments<\/p>\n

Jean-Marie FONTENEAU Philippe KLUSIEWICZ<\/p>\n

Exp. Pharm. Ahmet Nezihi Pekcan
\nPekcan Pharmacy – Konya
\npekcanecz@gmail.com
\nTel: (332) 3520657http:\/\/www.majistralformul.com\/<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Cosmesis”; in the Greek language, means “The Art of Beautification“. The role of cosmetics can generally be defined this way as well. However, today this definition is losing its adequacy; […]<\/p>\n","protected":false},"author":1,"featured_media":1967,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_members_access_role":[],"_members_access_error":""},"doc_category":[159],"doc_tag":[],"class_list":["post-9377","docs","type-docs","status-publish","has-post-thumbnail","hentry","doc_category-general-articles"],"acf":[],"year_month":"2026-09","word_count":860,"total_views":"2","reactions":{"happy":"0","normal":"0","sad":"0"},"author_info":{"name":"m921a","author_nicename":"m921a","author_url":"https:\/\/majistraleczacilari.org.tr\/en\/author\/m921a\/"},"doc_category_info":[{"term_name":"General Articles","term_url":"https:\/\/majistraleczacilari.org.tr\/en\/dokuman-kategori\/general-articles\/"}],"doc_tag_info":[],"knowledge_base_info":[],"knowledge_base_slug":[],"_links":{"self":[{"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/docs\/9377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/docs"}],"about":[{"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/types\/docs"}],"author":[{"embeddable":true,"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/comments?post=9377"}],"version-history":[{"count":1,"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/docs\/9377\/revisions"}],"predecessor-version":[{"id":9379,"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/docs\/9377\/revisions\/9379"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/media\/1967"}],"wp:attachment":[{"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/media?parent=9377"}],"wp:term":[{"taxonomy":"doc_category","embeddable":true,"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/doc_category?post=9377"},{"taxonomy":"doc_tag","embeddable":true,"href":"https:\/\/majistraleczacilari.org.tr\/en\/wp-json\/wp\/v2\/doc_tag?post=9377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}